Esophageal Cancer Doctor in Indore

Esophageal Cancer is a type of cancer that starts in the lining of the uterus (endometrium) and is the most common gynecological cancer. It is often detected early due to noticeable symptoms like abnormal vaginal bleeding, which enables effective treatment in many cases.

Common Types of Esophageal Cancer

• Type I (Endometrioid adenocarcinoma): The most common type, usually estrogen-dependent, with generally a favorable prognosis. Subtypes include villoglandular, secretory, and those with squamous differentiation.

• Type II (Serous, clear cell, and other high-grade carcinomas): Less common, more aggressive, and often not linked to excess estrogen.

• Other rare forms include adenosquamous carcinoma, uterine carcinosarcoma, pure squamous cell carcinoma, and clear cell carcinoma.

Symptoms

• Abnormal vaginal bleeding (especially after menopause).

• Bleeding between periods (in premenopausal women).

• Unpleasant watery or discolored vaginal discharge.

• Pelvic or abdominal pain.

• Difficulty urinating, changes in bowel habits, or unexplained weight loss (less common).

Risk Factors

• Increasing age (most cases occur in women over 50 and after menopause).

• Obesity, diabetes, and high blood pressure.

• Long-term estrogen exposure (e.g., hormone therapy without progesterone, early menstruation, late menopause, never having been pregnant).

• Family history of endometrial or colorectal cancer (especially Lynch syndrome).

• Polycystic ovary syndrome (PCOS) and tamoxifen use (used in breast cancer therapy).

Prevention

• Maintaining a healthy weight and regular physical activity.

• Managing diabetes and hypertension.

• Use of combined oral contraceptives (provides some protective effect).

• Regular medical checkups, especially for those with higher risk, and prompt evaluation of any abnormal vaginal bleeding.

• Genetic counseling and risk-reducing strategies for women with Lynch syndrome or a family history.

Early recognition of symptoms—especially abnormal bleeding after menopause—plays a critical role in early diagnosis and better outcomes for endometrial cancer.